Smith (Sm) Antibodies

Anti-Sm antibodies target the Sm antigen, a protein component of the spliceosome. They are highly specific for systemic lupus erythematosus (SLE).

Category: Inflammation & Immune

Also known as: smith antibodies

Reference range: 0–0.9 AI (Source: ABIM)

Standard unit: AI

High values may indicate

Positive anti-Sm antibodies are highly specific (though not highly sensitive) for SLE.

Low values may indicate

Negative result. Low likelihood of SLE based on this marker alone.

Frequently asked questions

What is a normal Smith (Sm) Antibodies level?
A typical reference range for Smith (Sm) Antibodies is 0–0.9 AI (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
What units is Smith (Sm) Antibodies measured in?
Smith (Sm) Antibodies is most commonly reported in AI. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
Where do Smith (Sm) Antibodies reference ranges come from?
BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
Can I track Smith (Sm) Antibodies over time?
Yes. Upload results from any lab and BloodId charts your Smith (Sm) Antibodies over time against its reference range, so you can see whether the trend is rising, falling, or stable.

Related biomarkers

Source: BloodId admin-reviewed

How we source our data

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