Anti-CCP
Anti-CCP (anti-cyclic citrullinated peptide) antibodies are autoantibodies that target citrullinated proteins. This test is highly specific for rheumatoid arthritis and can detect it early, often bef…
Category: Inflammation & Immune
Also known as: anti-ccp, anti ccp, cyclic citrullinated peptide antibody, ccp antibody, accp, anti-cyclic citrullinated peptide
Reference range: 0–20 U/mL (Source: ABIM)
Standard unit: U/mL
High values may indicate
High anti-CCP levels strongly suggest rheumatoid arthritis. Higher levels are associated with more severe joint damage and disease progression.
Low values may indicate
Low or negative anti-CCP levels make rheumatoid arthritis less likely, though some RA patients may be anti-CCP negative (seronegative RA).
Frequently asked questions
- What is a normal Anti-CCP level?
- A typical reference range for Anti-CCP is 0–20 U/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Anti-CCP measured in?
- Anti-CCP is most commonly reported in U/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Anti-CCP reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Anti-CCP over time?
- Yes. Upload results from any lab and BloodId charts your Anti-CCP over time against its reference range, so you can see whether the trend is rising, falling, or stable.