Anti-CCP (anti-cyclic citrullinated peptide) antibodies are autoantibodies that target citrullinated proteins. This test is highly specific for rheumatoid arthritis and can detect it early, often bef…
Category: Inflammation & Immune
Also known as: anti-ccp, anti ccp, cyclic citrullinated peptide antibody, ccp antibody, accp, anti-cyclic citrullinated peptide
Reference range: 0–20 U/mL (Source: ABIM)
Standard unit: U/mL
High values may indicate
High anti-CCP levels strongly suggest rheumatoid arthritis. Higher levels are associated with more severe joint damage and disease progression.
Low values may indicate
Low or negative anti-CCP levels make rheumatoid arthritis less likely, though some RA patients may be anti-CCP negative (seronegative RA).