Complement C3 is a protein that is part of the complement system, a group of proteins that work together to support the immune response. C3 is the most abundant complement protein in the blood.
Category: Inflammation & Immune
Also known as: complement c3, c3, c3 complement, serum c3
Reference range: 90–180 mg/dL (Source: ABIM)
Standard unit: mg/dL
High values may indicate
High C3 levels may indicate acute inflammation, infection, or certain cancers. C3 acts as an acute phase reactant that increases during inflammatory responses.
Low values may indicate
Low C3 levels may indicate systemic lupus erythematosus (SLE), glomerulonephritis, severe liver disease, inherited complement deficiency, or active autoimmune disease consuming complement proteins.