CH50 (Total Complement)
CH50 (total hemolytic complement) measures the overall functional activity of the entire classical complement pathway. It evaluates whether all complement proteins (C1 through C9) are working properl…
Category: Inflammation & Immune
Also known as: ch50, total complement, complement total, total hemolytic complement, ch 50, Total Hem Comp
Reference range: 30–75 U/mL (Source: ABIM)
Standard unit: U/mL
High values may indicate
High CH50 levels may indicate acute inflammation, infection, or certain cancers, as complement proteins can increase during acute phase responses.
Low values may indicate
Low CH50 levels may indicate complement deficiency (inherited or acquired), active autoimmune diseases (especially lupus), immune complex diseases, or severe liver disease that impairs complement production.
Frequently asked questions
- What is a normal CH50 (Total Complement) level?
- A typical reference range for CH50 (Total Complement) is 30–75 U/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is CH50 (Total Complement) measured in?
- CH50 (Total Complement) is most commonly reported in U/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do CH50 (Total Complement) reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track CH50 (Total Complement) over time?
- Yes. Upload results from any lab and BloodId charts your CH50 (Total Complement) over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: MedlinePlus, U.S. National Library of Medicine
Analyze your CH50 (Total Complement) with AI