Anti-tTG IgA
Anti-tissue transglutaminase IgA (anti-tTG IgA) is the primary screening antibody for celiac disease. It targets the enzyme tissue transglutaminase, which is involved in the immune response to gluten.
Category: Inflammation & Immune
Also known as: anti-ttg iga, anti ttg iga, tissue transglutaminase iga, anti-tissue transglutaminase iga, ttg iga, ttg-iga, antitela prema tkivnoj transglutaminazi iga
Reference range: 0–4 U/mL (Source: ABIM)
Standard unit: U/mL
High values may indicate
High anti-tTG IgA levels strongly suggest celiac disease or dermatitis herpetiformis. Further evaluation with intestinal biopsy may be recommended.
Low values may indicate
Low or negative anti-tTG IgA levels make celiac disease unlikely, though IgA deficiency should be ruled out.
Frequently asked questions
- What is a normal Anti-tTG IgA level?
- A typical reference range for Anti-tTG IgA is 0–4 U/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Anti-tTG IgA measured in?
- Anti-tTG IgA is most commonly reported in U/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Anti-tTG IgA reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Anti-tTG IgA over time?
- Yes. Upload results from any lab and BloodId charts your Anti-tTG IgA over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: MedlinePlus, U.S. National Library of Medicine
Analyze your Anti-tTG IgA with AI