Anti-tissue transglutaminase IgA (anti-tTG IgA) is the primary screening antibody for celiac disease. It targets the enzyme tissue transglutaminase, which is involved in the immune response to gluten.
Category: Inflammation & Immune
Also known as: anti-ttg iga, anti ttg iga, tissue transglutaminase iga, anti-tissue transglutaminase iga, ttg iga, ttg-iga, antitela prema tkivnoj transglutaminazi iga
Reference range: 0–4 U/mL (Source: ABIM)
Standard unit: U/mL
High values may indicate
High anti-tTG IgA levels strongly suggest celiac disease or dermatitis herpetiformis. Further evaluation with intestinal biopsy may be recommended.
Low values may indicate
Low or negative anti-tTG IgA levels make celiac disease unlikely, though IgA deficiency should be ruled out.