Anti-Scl-70 (Topoisomerase I) Antibodies
Anti-Scl-70 (anti-topoisomerase I) antibodies are associated with diffuse cutaneous systemic sclerosis (scleroderma) and are a marker for interstitial lung disease in these patients.
Category: Inflammation & Immune
Also known as: antiscleroderma-70 antibodies
Reference range: 0–0.9 AI (Source: ABIM)
Standard unit: AI
High values may indicate
Elevated anti-Scl-70 antibodies are associated with diffuse systemic sclerosis and increased risk of interstitial lung disease.
Low values may indicate
Negative or low result. Less likely to have Scl-70-associated scleroderma.
Frequently asked questions
- What is a normal Anti-Scl-70 (Topoisomerase I) Antibodies level?
- A typical reference range for Anti-Scl-70 (Topoisomerase I) Antibodies is 0–0.9 AI (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Anti-Scl-70 (Topoisomerase I) Antibodies measured in?
- Anti-Scl-70 (Topoisomerase I) Antibodies is most commonly reported in AI. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Anti-Scl-70 (Topoisomerase I) Antibodies reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Anti-Scl-70 (Topoisomerase I) Antibodies over time?
- Yes. Upload results from any lab and BloodId charts your Anti-Scl-70 (Topoisomerase I) Antibodies over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: BloodId admin-reviewed
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