Anti-dsDNA
Anti-dsDNA (anti-double-stranded DNA) antibodies are autoantibodies that target the body's own DNA. They are highly specific for systemic lupus erythematosus (SLE).
Category: Inflammation & Immune
Also known as: anti-dsdna, anti dsdna, double stranded dna antibody, anti-double stranded dna, dsdna antibody, ds-dna antibody, anti-dsdnk
Reference range: 0–30 IU/mL (Source: ABIM)
Standard unit: IU/mL
High values may indicate
High anti-dsDNA levels strongly suggest systemic lupus erythematosus (SLE). Rising levels often correlate with lupus disease activity, particularly lupus nephritis (kidney involvement).
Low values may indicate
Low or negative anti-dsDNA levels make lupus less likely but do not entirely rule it out. Levels may decrease during periods of disease remission.
Frequently asked questions
- What is a normal Anti-dsDNA level?
- A typical reference range for Anti-dsDNA is 0–30 IU/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Anti-dsDNA measured in?
- Anti-dsDNA is most commonly reported in IU/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Anti-dsDNA reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Anti-dsDNA over time?
- Yes. Upload results from any lab and BloodId charts your Anti-dsDNA over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: MedlinePlus, U.S. National Library of Medicine
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