UIBC

Unsaturated Iron Binding Capacity (UIBC) measures the reserve capacity of transferrin to bind additional iron. It equals TIBC minus serum iron.

Category: Iron Studies

Also known as: uibc, unsaturated iron binding capacity, unsaturated iron-binding capacity, latent iron binding capacity

Reference range: 111–343 µg/dL (Source: ABIM)

Standard unit: µg/dL

High values may indicate

High UIBC may indicate iron deficiency, as more transferrin binding sites are available to capture iron.

Low UIBC may indicate iron overload (hemochromatosis), chronic inflammation, or liver disease.