SHBG (sex hormone-binding globulin) is a protein produced by the liver that binds to sex hormones (testosterone, estradiol, DHT) and controls how much is available for your body to use.
Category: Hormones
Also known as: shbg, sex hormone binding globulin, sex hormone-binding globulin
Reference range: 10–57 nmol/L (Source: ABIM)
Standard unit: nmol/L
High values may indicate
High SHBG levels may indicate hyperthyroidism, liver disease, anorexia nervosa, estrogen excess, or aging, and can reduce the amount of free (active) testosterone available.
Low values may indicate
Low SHBG levels may indicate obesity, type 2 diabetes, hypothyroidism, polycystic ovary syndrome (PCOS), or androgen excess, and can increase the amount of free testosterone.