Renin is an enzyme produced by the kidneys that plays a key role in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure, fluid balance, and electrolyte levels.
Category: Hormones
Also known as: renin, plasma renin activity, pra, renin activity, active renin, direct renin
Reference range: 0.5–3.5 ng/mL/hr (Source: ABIM)
Standard unit: ng/mL/hr
High values may indicate
High renin levels may indicate renovascular hypertension, kidney disease, dehydration, heart failure, Addison's disease, or use of diuretics and ACE inhibitors.
Low values may indicate
Low renin levels may indicate primary aldosteronism (Conn's syndrome), excess salt intake, or use of certain antihypertensive medications such as beta-blockers.