IGF-1 (insulin-like growth factor 1) is a hormone produced primarily by the liver in response to growth hormone. It mediates many of the growth-promoting effects of growth hormone on bones, muscles,…
Category: Hormones
Also known as: igf-1, igf1, insulin-like growth factor 1, insulin like growth factor, somatomedin c
Reference range: 100–400 ng/mL (Source: ABIM)
Standard unit: ng/mL
High values may indicate
High IGF-1 levels may indicate acromegaly (excess growth hormone in adults), gigantism in children, or growth hormone-secreting pituitary tumors.
Low values may indicate
Low IGF-1 levels may indicate growth hormone deficiency, pituitary disorders, liver disease, malnutrition, or hypothyroidism, and can contribute to short stature in children and muscle weakness in adults.