Estrone (E1)
Estrone (E1) is a form of estrogen primarily produced in fat tissue. It is the dominant estrogen in postmenopausal women and plays a role in reproductive health and bone metabolism.
Category: Hormones
Also known as: estrone, e1, oestrone, estron
Reference range: 10–60 pg/mL (Source: ABIM)
Standard unit: pg/mL
High values may indicate
High estrone levels may indicate obesity (increased aromatase activity in fat tissue), estrogen-producing tumors, liver disease, or hormone replacement therapy.
Low values may indicate
Low estrone levels may indicate ovarian insufficiency, menopause, anorexia nervosa, or pituitary disorders, and can contribute to bone loss and menopausal symptoms.
Frequently asked questions
- What is a normal Estrone (E1) level?
- A typical reference range for Estrone (E1) is 10–60 pg/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Estrone (E1) measured in?
- Estrone (E1) is most commonly reported in pg/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Estrone (E1) reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Estrone (E1) over time?
- Yes. Upload results from any lab and BloodId charts your Estrone (E1) over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: MedlinePlus, U.S. National Library of Medicine
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