Estradiol (E2)
Estradiol (E2) is the most potent form of estrogen and is primarily produced by the ovaries in women and in smaller amounts by the testes in men. It plays a key role in reproductive health and bone d…
Category: Hormones
Also known as: estradiol, e2, estrogen, oestradiol, 17-beta estradiol
Reference range: 10–40 pg/mL (Source: ABIM)
Standard unit: pg/mL
High values may indicate
High estradiol levels may indicate ovarian tumors, liver cirrhosis, hyperthyroidism, estrogen-producing adrenal tumors, or use of estrogen-containing medications. In men, elevated levels may cause gynecomastia.
Low values may indicate
Low estradiol levels may indicate ovarian failure, menopause, polycystic ovary syndrome, eating disorders, or pituitary disorders, and can lead to osteoporosis, irregular periods, and infertility.
Frequently asked questions
- What is a normal Estradiol (E2) level?
- A typical reference range for Estradiol (E2) is 10–40 pg/mL (source: ABIM). Reference ranges vary by laboratory, age, and sex, so always compare against the range on your own lab report.
- What units is Estradiol (E2) measured in?
- Estradiol (E2) is most commonly reported in pg/mL. Labs in different countries may use other units — you can convert between them with BloodId's blood test unit converter.
- Where do Estradiol (E2) reference ranges come from?
- BloodId uses ABIM standard reference ranges and educational information from MedlinePlus (see our methodology). Reference ranges still vary by lab, age, and sex, so always compare against your own report.
- Can I track Estradiol (E2) over time?
- Yes. Upload results from any lab and BloodId charts your Estradiol (E2) over time against its reference range, so you can see whether the trend is rising, falling, or stable.
Related biomarkers
Source: MedlinePlus, U.S. National Library of Medicine
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