Estradiol (E2) is the most potent form of estrogen and is primarily produced by the ovaries in women and in smaller amounts by the testes in men. It plays a key role in reproductive health and bone d…
Category: Hormones
Also known as: estradiol, e2, estrogen, oestradiol, 17-beta estradiol
Reference range: 10–40 pg/mL (Source: ABIM)
Standard unit: pg/mL
High values may indicate
High estradiol levels may indicate ovarian tumors, liver cirrhosis, hyperthyroidism, estrogen-producing adrenal tumors, or use of estrogen-containing medications. In men, elevated levels may cause gynecomastia.
Low values may indicate
Low estradiol levels may indicate ovarian failure, menopause, polycystic ovary syndrome, eating disorders, or pituitary disorders, and can lead to osteoporosis, irregular periods, and infertility.